Histamine, paroxysmal AV block and low adenosine syncope a case report.

Wansa, Nader;Goethals, Peter;De Roy, Luc
(2018) Journal of Electrocardiology — Vol. 51, n° 1, p. 150-152 (2018)

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  • Wansa, Nader
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  • Goethals, Peter
    Author
  • De Roy, LucUCLouvain
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Abstract
(en) Histamine is a widespread natural amine, rarely suspected to provoke syncope due to complete atrio-ventricular block. A patient was admitted to the emergency room after an episode of vomiting and syncope following a dinner of mussels, most likely attributable to a histamine food intoxication. Stale mussels are ostensibly known to occasionally encompass high concentrations of histamine. We hereby present, a documented unexpected complete atrioventricular block (AV block) with preserved stable sinus electrical activity during an episode of fainting with vomiting. Pathophysiologically, we hypothesize a possible intense H1 and/or A1 receptor stimulation linked to histamine overload, suggestive of a variant of idiopathic AVB or low adenosine syncope.
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Wansa, N., Goethals, P., & De Roy, L. (2018). Histamine, paroxysmal AV block and low adenosine syncope a case report. Journal of Electrocardiology, 51(1), 150-152. https://doi.org/10.1016/j.jelectrocard.2017.09.003 (Original work published 2018)