Wheat germ in vitro translation to produce one of the most toxic sodium channel specific toxins

Gad, Wael;Messens, Joris;Bouhaouala-Zahar, Balkiss;Muyldermans, Serge;Ben-Abderrazek, Rahma;et.al.
(2014) Bioscience Reports : molecular and cellular biology of the cell surface — Vol. 34, n° 4, p. 369-379 (2014)

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Authors
  • Gad, Wael
    Author
  • Messens, Joris
    Author
  • Bouhaouala-Zahar, Balkiss
    Author
  • Muyldermans, Serge
    Author
  • Vertommen, Didierorcid-logoUCLouvain
    Author
  • Ben-Abderrazek, Rahma
    Author
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Abstract
of 3 ng) indicates that the wheat germ in vitro translation system produces properly folded and biological active rAahII. In addition, NbAahII10 (Androctonus australis hector nanobody 10), a camel single domain antibody fragment, raised against the native AahII toxin, recognizes its cognate conformational epitope on the recombinant toxin and neutralizes the toxicity of purified rAahII upon injection in mice. © 2014 The Author(s).
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Gad, W., Messens, J., Bouhaouala-Zahar, B., Muyldermans, S., Vertommen, D., Wahni, K., & Ben-Abderrazek, R. (2014). Wheat germ in vitro translation to produce one of the most toxic sodium channel specific toxins. Bioscience Reports : molecular and cellular biology of the cell surface, 34(4), 369-379. https://doi.org/10.1042/BSR20140050 (Original work published 2014)