Despite decades of clinical research aimed at finding the most appropriate immunosuppressive regime, lupus nephritis (LN) remains one of the major disease manifestations of systemic lupus erythematosus (SLE) with a great impact on survival and quality of life. We start this review by defining the disease burden, the real-world challenges and the poor prognostic factors. We then discuss the current anti-inflammatory, cytotoxic and biologic therapies, with special emphasis on the need for optimal global care.
Houssiau, F., & Lauwerys, B. (2013). Current management of lupus nephritis. Best Practice & Research: Clinical Rheumatology, 27(3), 319-328. https://doi.org/10.1016/j.berh.2013.07.004 (Original work published 2013)