Nouvelles méthodologies pour la préparation de jérangolides et analogues
(2016)
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- Authors
- Supervisors
- Marko, Istvan
- Abstract
- During this last decade, a large growth in fungal infections has been observed1, resulting, not only from the increase in immunodeficient patients but also from the capacity of the fungal microorganisms to acquire resistance towards current drugs. In 1991, the natural compounds Jerangolid A, B, D, E and H have been isolated and Jerangolid A found to display interesting antifungal properties against several fungal strains. With the aim of developing a new type of potential antifungal drug, it was decided to assemble the natural Jerangolids and some analogs. To facilitate and accelerate these syntheses, we developed various original synthetic methodologies.
- Affiliations
Citations
Debrus, K. (2016). Nouvelles méthodologies pour la préparation de jérangolides et analogues. https://hdl.handle.net/2078.5/61643