Today's treatments: medical, surgical and in partnership.
(1999) International Journal of Gynecology & Obstetrics — Vol. 64 Suppl 1, p. S5-13 (1999)
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- Abstract
- OBJECTIVE: To provide an overview of the medical, surgical and combined therapy options for endometriosis. RESULTS: Available medical options include danazol, progestogens, gestrinone, oral contraceptive agents, analgesics and gonadotropin-releasing hormone (GnRH) agonists. Used in the short-term, most of these agents relieve pain in a large proportion of patients and produce disease regression, however, they do not prevent recurrence, and are associated with side-effects. However, few data confirm any benefit of short-term medical therapy on fertility. One of the most promising medical approaches appears to be GnRH agonists with add-back hormone replacement therapy. Surgery may relieve pain, eradicate visible disease and improve fertility. A combined approach may facilitate surgery and relieve pain, although any fertility benefit is as yet unproven. CONCLUSION: Both short-term medical treatment and surgery relieve endometriosis-associated pain and decrease endometriotic implants. However, all approaches have side effects which must be balanced against the benefits when defining suitable treatment for a particular patient.
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Donnez, J. (1999). Today’s treatments: medical, surgical and in partnership. International Journal of Gynecology & Obstetrics, 64 Suppl 1, S5-13. https://doi.org/10.1016/S0020-7292(98)00236-7 (Original work published 1999)