Signal transduction molecule patterns indicating potential glioblastoma therapy approaches.
(2013) OncoTargets and Therapy — Vol. 6, n° 29, p. 1737-1749 (2013)
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- Abstract
- The expression of an array of signaling molecules, along with the assessment of real-time cell proliferation, has been performed in U87 glioma cell line and in patients' glioblastoma established cell cultures in order to provide a better understanding of cellular and molecular events involved in glioblastoma pathogenesis. Experimental therapy was performed using a phosphatidylinositol-3'-kinase (PI3K) inhibitor.
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Cruceru, M. L., Enciu, A.-M., Popa, A. C., Albulescu, R., Neagu, M., Tanase, C. P., & Constantinescu, S. (2013). Signal transduction molecule patterns indicating potential glioblastoma therapy approaches. OncoTargets and Therapy, 6(29), 1737-1749. https://doi.org/10.2147/OTT.S52365 (Original work published 2013)