Identification of a novel HLA-Cw*05 allele, Cw*0503
(2000) Tissue Antigens : immune response genetics — Vol. 55, n° 5, p. 473-474 (2000)
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- Abstract
- HLA-Cw*05 is one of the least polymorphic subgroups of HLA-C; so far only two alleles, namely Cw*0501 and Cw*0502, have been reported. We report here the identification of a third allele, Cw*0503, in a Caucasian individual. Cw*0503 is closely related to Cw*0501 with only six nucleotide substitutions clustering over a fragment of 48 nucleotides at the beginning of exon 4. All these six substitutions at the same positions have been found only in HLA-B*44 alleles, suggesting that Cw*0503 is a result of recombination between Cw*0501 and one of B*44 alleles.
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Huang, L., Boon, T., & Van Pel, A. (2000). Identification of a novel HLA-Cw*05 allele, Cw*0503. Tissue Antigens : immune response genetics, 55(5), 473-474. https://doi.org/10.1034/j.1399-0039.2000.550515.x (Original work published 2000)