Multiple oligomerization domains of KANK1-PDGFRβ are required for JAK2-independent hematopoietic cell proliferation and signaling via STAT5 and ERK.

Medves, Sandrine;Noël, Laura A;Montano-Almendras, Carmen P;Albu, Roxana I;Demoulin, Jean Baptiste;et.al.
(2011) Haematologica : the hematology journal — Vol. 96, n° 10, p. 1406-1414 (2011)

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Abstract
KANK1-PDGFRB is a unique example of a thrombocythemia-associated oncogene that does not signal via JAK2. The fusion protein is activated by multiple oligomerization domains, which are required for signaling and cell growth stimulation.
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Medves, S., Noël, L. A., Montano-Almendras, C. P., Albu, R. I., Schoemans, H., Constantinescu, S., & Demoulin, J. B. (2011). Multiple oligomerization domains of KANK1-PDGFRβ are required for JAK2-independent hematopoietic cell proliferation and signaling via STAT5 and ERK. Haematologica : the hematology journal, 96(10), 1406-1414. https://doi.org/10.3324/haematol.2011.040147 (Original work published 2011)