PD is a negative prognostic factor, but it is not an absolute contraindication to LR. Patients with PD could be scheduled for LR except for those with >3 metastases and ≥50 mm, or CEA ≥200 ng/mL in whom further chemotherapy is recommended.
Viganò, L., Capussotti, L., Barroso, E., Nuzzo, G., Laurent, C., Ijzermans, J. N. M., Gigot, J.-F., Figueras, J., Gruenberger, T., Mirza, D. F., Elias, D., Poston, G., Letoublon, C., Isoniemi, H., Herrera, J., Castro Sousa, F., Pardo, F., Lucidi, V., Popescu, I., & Adam, R. (2012). Progression while Receiving Preoperative Chemotherapy Should Not Be an Absolute Contraindication to Liver Resection for Colorectal Metastases. Annals of Surgical Oncology, 19(9), 2786-2796. https://doi.org/10.1245/s10434-012-2382-7 (Original work published 2012)