To evaluate HIV-2 RNA quantification assays used in nine laboratories of the ACHIEV2E group. In a blinded experimental design, laboratories quantified three series of aliquots of HIV-2 subtype A strain, each at a different theoretical viral load. Quantification varied between laboratories and international standardization of quantification assays is strongly needed.
Damond, F., Benard, A., Ruelle, J., Alabi, A., Kupfer, B., Gomes, P., Rodes, B., Albert, J., Böni, J., Garson, J., Ferns, B., Matheron, S., Chene, G., & Brun-Vezinet, F. (2008). Quality control assessment of HIV-2 viral load quantification assays. Results from an international collaboration on HIV-2 infection, 2006. Journal of Clinical Microbiology, 46(6), 2088-2091. https://doi.org/10.1128/JCM.00126-08 (Original work published 2008)