Intraperitoneal administration of novel doxorubicin loaded polymeric delivery systems against peritoneal carcinomatosis: experimental study in a murine model of ovarian cancer.
(2011) Gynecologic Oncology — Vol. 122, n° 3, p. 632-640 (2011)
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- Abstract
- P-HYD-DOX conjugates demonstrated significant activity against peritoneal carcinomatosis in a xenograft model of ovarian carcinomatosis and their ability to release active DOX in i.p. deposits and tumor. These features are of clinical interest for i.p. administration in the treatment of ovarian peritoneal carcinomatosis after cytoreductive surgery.
Citations
Colombo, P.-E., Boustta, M., Poujol, S., Jarlier, M., Bressolle, F., Teulon, I., Ladjemi, M.-Z., Pinguet, F., Rouanet, P., & Vert, M. (2011). Intraperitoneal administration of novel doxorubicin loaded polymeric delivery systems against peritoneal carcinomatosis: experimental study in a murine model of ovarian cancer. Gynecologic Oncology, 122(3), 632-640. https://doi.org/10.1016/j.ygyno.2011.05.032 (Original work published 2011)