AOPs to connect food additives’ effects on gut microbiota to health outcomes
(2025) Altex — Vol. 42, n° 2, p. 257-262 (2025)
Files
altex_2025_2_257_262_Clerbaux.pdf
Open Access - Adobe PDF
- 714.72 KB
Details
- Authors
- Abstract
- (en) Plain language summary The microorganisms in our gut release molecules that influence our body functions and keep us healthy. Food additives, which are used to enhance the texture, preservation and appearance of foods, may disrupt the microbial balance, potentially leading to detrimental health effects. However, the potential impact of food additives on gut microorganisms is not yet considered in their safety assessments. Developing human-based tests to study these interactions could inform the safety assessment of food additives. The adverse outcome pathway (AOP) framework allows compiling and structuring relevant information and identifying knowledge gaps. Using human-based tests rather than animal tests yields more relevant results and reduces the reliance on animal testing in toxicology research.
- Affiliations
Citations
Clerbaux, L.-A. (2025). AOPs to connect food additives’ effects on gut microbiota to health outcomes. Altex, 42(2), 257-262. https://doi.org/10.14573/altex.2411271 (Original work published 2025)