Cadmium, lead and endometriosis.

Heilier, Jean-François;Donnez, Olivier;Donnez, Jacques;Verougstraete, Violaine;Lison, Dominique;et.al.
(2006) International Archives of Occupational and Environmental Health — Vol. 80, n° 2, p. 149-153 (2006)

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Abstract
OBJECTIVES: Cadmium (Cd) and lead (Pb) have been demonstrated to exert endocrine disrupting activities. Their possible role in endometriosis, an oestrogen-dependent disease, is unknown. METHODS: We compared cadmium urinary excretion (CdU) and blood concentration of cadmium (CdB) and lead (PbB) in 119 patients with peritoneal endometriosis and/or deep endometriotic (adenomyotic) nodules of the rectovaginal septum and 25 controls. RESULTS: The mean levels of cadmium in urine and blood did not differ among the groups. Women suffering from endometriotic diseases showed lower levels of PbB than controls. CONCLUSIONS: These data do not support a role for cadmium in the onset or the growth of endometriotic diseases but suggest a possible relationship with lead.
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Heilier, J.-F., Donnez, O., Donnez, J., Verougstraete, V., Grandjean, F., Haufroid, V., Nackers, F., & Lison, D. (2006). Cadmium, lead and endometriosis. International Archives of Occupational and Environmental Health, 80(2), 149-153. https://doi.org/10.1007/s00420-006-0114-7 (Original work published 2006)