Manifestations rares des gammapathies monoclonales : à propos de 2 cas et revue de la littérature

Perlot, Quentin;Hermans, Cédric;Vekemans, Marie-Christiane
(2023) La Revue de médecine interne — Vol. 44, n° 6, p. 307-310 (2023)

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Abstract
(en) [Rare manifestations of monoclonal gammopathies: About two clinical cases and literature review]. INTRODUCTION: Monoclonal gammopathies are common over the age of 50. Patients are usually asymptomatic. However, some patients present with secondary clinical manifestations, which are now grouped under the entity « Monoclonal Gammopathy of Clinical Significance » (MGCS). CASE REPORT: Here, we report two rare cases of MGCS: an acquired von Willebrand syndrome (AvWS) and an acquired angioedema (AAE). CONCLUSION: The discovery of a decrease in von Willebrand activity (vWF:RCo) or angioedema in a patient over 50 years of age, in the absence of a family history, should prompt a search for a hemopathy and in particular, a monoclonal gammopathy.
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Perlot, Q., Hermans, C., & Vekemans, M.-C. (2023). Manifestations rares des gammapathies monoclonales : à propos de 2 cas et revue de la littérature. La Revue de médecine interne, 44(6), 307-310. https://doi.org/10.1016/j.revmed.2023.03.005 (Original work published 2023)