First epileptic seizure induced by occupational nickel poisoning.

Denays, Roger;Kumba, Claudine;Lison, Dominique;De Bels, David
(2005) Epilepsia — Vol. 46, n° 6, p. 961-962 (2005)

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Authors
  • Denays, Roger
    Author
  • Kumba, Claudine
    Author
  • Lison, Dominiqueorcid-logoUCLouvain
    Author
  • De Bels, David
    Author
Abstract
Toxic causes of seizures are numerous: alcohol and other substances of abuse, drugs, and industrial and household products. However, in the absence of a clearly suggestive history and/or associated symptoms and signs, identification of the toxic origin of new-onset seizures may be extremely difficult. We report here the case of a patient admitted in our hospital after a single generalized tonic-clonic seizure. The remarkable coincidence that a colleague of his, with whom he was working to clean the same workshop, had been admitted 1 week earlier for respiratory distress, coma, and de novo nonconvulsive focal status epilepticus, led us to consider a possible toxicologic etiology. Urine analysis revealed a high nickel concentration, suggestive of acute nickel poisoning.
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Denays, R., Kumba, C., Lison, D., & De Bels, D. (2005). First epileptic seizure induced by occupational nickel poisoning. Epilepsia, 46(6), 961-962. https://doi.org/10.1111/j.1528-1167.2005.70004.x (Original work published 2005)