Outbreak of mumps in a vaccinated child population: a question of vaccine failure?

Vandermeulen, Corinne;Roelants, Mathieu;Vermoere, Marijke;Roseeuw, Katelijn;Hoppenbrouwers, Karel;et.al.
(2004) Vaccine — Vol. 22, n° 21-22, p. 2713-2716 (2004)

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Authors
  • Vandermeulen, Corinne
    Author
  • Roelants, Mathieu
    Author
  • Vermoere, Marijke
    Author
  • Roseeuw, Katelijn
    Author
  • Goubau, PatrickUCLouvain
    Author
  • Hoppenbrouwers, Karel
    Author
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Abstract
In Belgium, children are immunized against measles-mumps-rubella (MMR) in a two-dose schedule at the age of 15 months and 11 years. Despite these recommendations, epidemics of mumps still occur. During an outbreak of mumps in Bruges (Belgium), 105 cases were registered in seven schools (age group 3-12 years). Lower than optimal vaccination coverage, inadequate vaccination schedule and a combination of primary and/or secondary vaccine failure are considered as possible reasons for the outbreak as described in the article. The role of secondary vaccine failure is highlighted.
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Vandermeulen, C., Roelants, M., Vermoere, M., Roseeuw, K., Goubau, P., & Hoppenbrouwers, K. (2004). Outbreak of mumps in a vaccinated child population: a question of vaccine failure? Vaccine, 22(21-22), 2713-2716. https://doi.org/10.1016/j.vaccine.2004.02.001 (Original work published 2004)