Performance of age-adjusted D-dimer cut-off to rule out pulmonary embolism.

Penaloza-Baeza, Andrea;Roy, P-M;Kline, J;Verschuren, Franck;Thys, Frédéric;et.al.
(2012) Journal of thrombosis and haemostasis : JTH — Vol. 10, n° 7, p. 1291-1296 (2012)

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Abstract
Our study shows that age-adjusted D-dimer had low nLR, allowing its use as a rule-out PE strategy in non-high pretest clinical probability patients, as well as using Vidas(®), Liatest(®) or MDA(®) assays. This age-adjusted cut-off increased clinical usefulness of D-dimer in older patients. A large prospective study is required to confirm these results.
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Penaloza-Baeza, A., Roy, P.-M., Kline, J., Verschuren, F., LE Gal, G., Quentin-Georget, S., Delvau, N., & Thys, F. (2012). Performance of age-adjusted D-dimer cut-off to rule out pulmonary embolism. Journal of thrombosis and haemostasis : JTH, 10(7), 1291-1296. https://doi.org/10.1111/j.1538-7836.2012.04769.x (Original work published 2012)