It has been known for many years that cytolytic T lymphocytes that specifically recognize the tumor cells of the same patient can be derived from the blood of melanoma patients. Several of the antigens recognized by these antitumor T lymphocytes have now been completely identified. Some of them are sufficiently tumor-specific to envision their use as antitumor vaccines in selected cancer patients.
Coulie, P. (1995). Antigens Recognized On Human Tumors By Cytolytic T-lymphocytes - Towards Vaccination. Stem Cells : the international journal of cell differentiation and proliferation, 13(4), 393-403. https://doi.org/10.1002/stem.5530130410 (Original work published 1995)