The outcome after transjugular intrahepatic portosystemic shunt (TIPS) for hepatic hydrothorax is closely related to liver dysfunction: a long-term study in 28 patients.

Wilputte, Jean-Yves;Goffette, Pierre;Zech, Francis;Godoy-Gepert, Armando;Geubel, André
(2007) Acta Gastro-Enterologica Belgica (Multilingual Edition) — Vol. 70, n° 1, p. 6-10 (2007)

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Authors
  • Wilputte, Jean-Yves
    Author
  • Goffette, PierreUCLouvain
    Author
  • Zech, Francisorcid-logoUCLouvain
    Author
  • Godoy-Gepert, Armando
    Author
  • Geubel, AndréUCLouvain
    Author
Abstract
OBJECTIVES: Hepatic hydrothorax is a rare but challenging complication of cirrhosis. The Transjugular Intrahepatic Portosystemic Shunt (TIPS) appears as one of the most successful approach of therapy. METHODS: To assess long-term efficacy and safety, we reviewed 28 patients (Child B/C: 43/57%) who underwent TIPS placement for refractory hepatic hydrothorax in our institution between 1992 and 2001. RESULTS: The 30-days mortality was 14%, reaching 25% at 90 days. The one-year survival without liver transplantation was 41.2%. Reduction in the volume of pleural effusion and improvement in clinical symptoms was observed in 68% while a complete radiological and echographic disappearance of hydrothorax was documented in 57%. Statistical analysis showed that poor liver function was predictive of mortality and non-response. Of the different liver function parameters and in this small series, the Child-Pugh score was more discriminating than the recently described Mayo risk score. CONCLUSION: This study shows that TIPS is effective in the treatment of hepatic hydrothorax for selected patients. Poor liver function is a strong predictive of bad outcome.
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Wilputte, J.-Y., Goffette, P., Zech, F., Godoy-Gepert, A., & Geubel, A. (2007). The outcome after transjugular intrahepatic portosystemic shunt (TIPS) for hepatic hydrothorax is closely related to liver dysfunction: a long-term study in 28 patients. Acta Gastro-Enterologica Belgica (Multilingual Edition), 70(1), 6-10. https://hdl.handle.net/2078.5/211881 (Original work published 2007)