Circadian-rhythms in Cardiovascular-disease - the Crucial Hours

Detry, JMR.;Vincent, Marie-Françoise
(1992) SYMP ON PROTECTION DURING THE CRUCIAL HOURS : AMOLODIPINE, A NEW CALCIUM ANTAGONIST IN CARDIOVASCULAR DISEASE — Location: MONTREAL (Canada) (26.June.1990)

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Major cardiovascular events, i.e. myocardial infarction and sudden death, have a circadian variation with a peak incidence during the morning hours. The factors possibly triggering those events, namely myocardial ischaemia, sympathetic tone and blood coagulability, have a similar circadian variation which could explain the circadian distribution of the major cardiovascular events.
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Detry, JMR., & Vincent, M.-F. (1992). Circadian-rhythms in Cardiovascular-disease - the Crucial Hours. Journal of Human Hypertension, 6, S3-S8. https://hdl.handle.net/2078.5/42009 (Original work published 1992)