The present invention concerns the modulation of PRDM12 activity for prevention or treatment of pain in a subject. Both means to modify the expression level of PRDM12 and means to modify the PRDM12 activity are envisaged. The invention further relates to pharmaceutical compositions comprising a modulator of PRDM12 and to methods for diagnosing hypersensitivity to pain.
Bellefroid, E., Latragna, A., Vermeiren, S., Sabaté, A., Ris, L., & Gualdani, R. (2022). Modulation of PRDM12 for use in treatment of pain conditions. https://hdl.handle.net/2078.5/102136