Electrophysiological characterisation of myoclonic-atonic seizures in symptomatic continuous spike-waves during slow sleep syndrome.

Vrielynck, Pascal;Defresne, Pierre
(2009) Epileptic Disorders — Vol. 11, n° 1, p. 90-94 (2009)

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  • Vrielynck, Pascal
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  • Defresne, Pierre
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Abstract
Sudden epileptic falls are frequently reported in continuous spike-waves during slow sleep (CSWS) syndrome. Inhibitory seizures are usually considered as the underlying mechanism. However, published polygraphic recordings are rare. We report the case of a 22 month-old boy suffering from a symptomatic CSWS syndrome associated with a perinatal stroke involving the right middle cerebral artery territory. He presented with psychomotor regression and daily multiple falls related to myoclonic-atonic seizures. Neurophysiological examination showed secondary generalized myoclonus systematically correlated with a bilateral spike spreading from the right central area. This confirms that positive myoclonus, in addition to negative myoclonus, may be responsible for epileptic falls in CSWS syndrome. [Published with video sequences].
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Vrielynck, P., & Defresne, P. (2009). Electrophysiological characterisation of myoclonic-atonic seizures in symptomatic continuous spike-waves during slow sleep syndrome. Epileptic Disorders, 11(1), 90-94. https://doi.org/10.1684/epd.2009.0251 (Original work published 2009)