ST-segment-elevation myocardial infarction patients randomized to a pharmaco-invasive strategy or primary percutaneous coronary intervention: Strategic Reperfusion Early After Myocardial Infarction (STREAM) 1-year mortality follow-up.

Sinnaeve, Peter R;Armstrong, Paul W;Gershlick, Anthony H;Goldstein, Patrick;Meert, Philippe;et.al.
(2014) Circulation — Vol. 130, n° 14, p. 1139-1145 (2014)

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Authors
  • Sinnaeve, Peter R
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  • Armstrong, Paul W
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  • Gershlick, Anthony H
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  • Goldstein, Patrick
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  • Meert, PhilippeUCLouvain
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Abstract
In the Strategic Reperfusion Early After Myocardial Infarction (STREAM) trial, a pharmaco-invasive (PI) strategy was compared with primary percutaneous coronary intervention (pPCI) in ST-segment-elevation myocardial infarction patients presenting within 3 hours after symptom onset but unable to undergo pPCI within 1 hour. At 30 days, the PI approach was associated with a nominally but nonstatistically significant lower incidence of the composite primary end point of death, shock, congestive heart failure, and reinfarction when compared with pPCI. The aim of the present study was to determine the effect of these strategies on 1-year mortality.
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Sinnaeve, P. R., Armstrong, P. W., Gershlick, A. H., Goldstein, P., Wilcox, R., Lambert, Y., Danays, T., Soulat, L., Halvorsen, S., Ortiz, F. R., Vandenberghe, K., Regelin, A., Bluhmki, E., Bogaerts, K., Van de Werf, F., & Meert, P. (2014). ST-segment-elevation myocardial infarction patients randomized to a pharmaco-invasive strategy or primary percutaneous coronary intervention: Strategic Reperfusion Early After Myocardial Infarction (STREAM) 1-year mortality follow-up. Circulation, 130(14), 1139-1145. https://doi.org/10.1161/CIRCULATIONAHA.114.009570 (Original work published 2014)