Impedance sensing of polystyrene microspheres in a microfluidic channel: An integrated electrooptic method
(2019) E-MRS 2019 Spring Meeting — Location: Nice (France) (27.May.2019)
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- Abstract
- Electrical impedance measurements through microfluidic channels have been extensively studied over the last years, because electrical impedance is a simple and essentially a noninvasive technique that allows characterization of nano- and microparticles or other inorganic nano- and microstructuresin a dielectric medium. Electrical impedance sensing has successfully been used in flow cell cytometry, allowing the classification of different cell types. Here are presented results for polystyrene microspheres in a custom electrical impedance system composed of a modified commercial microfluidic channel along with optical micro-imaging characterization in an inverted microscope, quantifying the relationship between microspheres density, wavelength illumination range and magnitude of the electrical impedance signal for carboxyl and amino functionalized-microspheres in different fluid media. These observations are sustained by numerical modeling and discussed within a general theoretical framework. The obtained results might have potential application to classify novel nano- and micro-objects and further develop artificial intelligence-enabled drug delivery platforms.
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Caina Aysabucha, D. R., Avila Osses, J., & Melinte, S. (2019). Impedance sensing of polystyrene microspheres in a microfluidic channel: An integrated electrooptic method. E-MRS 2019 Spring Meeting, Nice (France). https://hdl.handle.net/2078.5/219423