Refining the definition of the malignant profile: insights from the DEFUSE-EPITHET pooled data set.

Mlynash, Michael;Lansberg, Maarten G;De Silva, Deidre A;Lee, Jun;Peeters, André;et.al.
(2011) Stroke : a journal of cerebral circulation — Vol. 42, n° 5, p. 1270-1275 (2011)

Files

2011-DEFUSE-EPITHETredefiningmalignantprofile.pdf
  • Restricted Access
  • Adobe PDF
  • 244.91 KB
Request a copy

Details

Authors
  • Mlynash, Michael
    Author
  • Lansberg, Maarten G
    Author
  • De Silva, Deidre A
    Author
  • Lee, Jun
    Author
  • Peeters, AndréUCLouvain
    Collaborator
Show more
Abstract
Stroke patients likely to suffer parenchymal hemorrhages and poor outcomes following reperfusion can be identified from baseline magnetic resonance imaging findings. The current analysis demonstrates that a PWI threshold (Tmax>8 s) of approximately 100 mL is appropriate for identifying these patients. Exclusion of malignant profile patients from reperfusion therapies may substantially improve the efficacy and safety of reperfusion therapies. Clinical Trial Registration Information- URL: http://www.clinicaltrials.gov. Unique identifier: NCT00238537.
Affiliations

Citations

  • APA
  • Chicago
  • FWB

Mlynash, M., Lansberg, M. G., De Silva, D. A., Lee, J., Christensen, S., Straka, M., Campbell, B. C. V., Bammer, R., Olivot, J.-M., Desmond, P., Donnan, G. A., Davis, S. M., & Albers, G. W. (2011). Refining the definition of the malignant profile: insights from the DEFUSE-EPITHET pooled data set. Stroke : a journal of cerebral circulation, 42(5), 1270-1275. https://doi.org/10.1161/STROKEAHA.110.601609 (Original work published 2011)