Transient complete remission of acute lymphoblastic leukemia in relapse after allogeneic bone marrow transplantation induced by donor leukocyte transfusions.

D'Hondt, Lionel;Chatelain, Christian;Doyen, Chantal;Osselaer, Jean-Claude;Bosly, André;et.al.
(1996) Hematology and Cell Therapy — Vol. 38, n° 4, p. 353-354 (1996)

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  • Author
  • Chatelain, ChristianUCLouvain
    Author
  • Doyen, Chantalorcid-logoUCLouvain
    Author
  • Osselaer, Jean-ClaudeUCLouvain
    Author
  • Bosly, AndréUCLouvain
    Author
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Abstract
We report the case of a young patient with refractory acute lymphoblastic leukemia relapse, after allogeneic bone marrow transplantation, who was treated by donor leukocyte infusions. We observed potent adoptive immunotherapy which produced a cytologic complete remission and total chimeric state. This was of short duration and the patient died of severe graft-versus-host disease. We present a short summary of the literature concerning acute lymphoblastic leukemia and donor leukocyte infusions.
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Citations

D’Hondt, L., Chatelain, C., Doyen, C., Osselaer, J.-C., Ferrant, A., & Bosly, A. (1996). Transient complete remission of acute lymphoblastic leukemia in relapse after allogeneic bone marrow transplantation induced by donor leukocyte transfusions. Hematology and Cell Therapy, 38(4), 353-354. https://doi.org/10.1007/s00282-996-0353-9 (Original work published 1996)