Use of an agent that restores tissue perfusion and oxygenation

Dewhirst, Mark W;Stamler, Jonathan S;McMahon, Timothy J;Sonveaux, Pierre
(2006)

Files

US7790204B2.pdf
  • Open Access
  • Adobe PDF
  • 2.33 MB
Download

Details

Authors
  • Dewhirst, Mark WDuke University Medical Center
    Inventor
  • Stamler, Jonathan SDuke University Medical Center
    Inventor
  • McMahon, Timothy JDuke University Medical Center
    Inventor
  • Sonveaux, PierreUCLouvain
    Inventor
Abstract
The presently disclosed subject matter provides methods for increasing perfusion in hypoxic regions of tissues in subjects. Also provided are methods for treating diseases and/or disorders associated with hypoxia in subjects, methods for increasing sensitivity of tumors to radiation and/or chemotherapy treatments, and/or other circulating antitumor treatments, diagnostic agents, and/or prognostic agents, methods for delaying tumor growth in subjects, and methods for inhibiting tumor blood vessel growth in subjects. Also provided are compositions that can be employed in the presently disclosed methods.
Affiliations

Citations

  • APA
  • Chicago
  • FWB

Dewhirst, M. W., Stamler, J. S., McMahon, T. J., & Sonveaux, P. (2006). Use of an agent that restores tissue perfusion and oxygenation (Patent No. 11/404,494). https://hdl.handle.net/2078.5/26729