Liver granulomatosis: a case of Chlamydophila pneumoniae infection.
(2015) Acta Clinica Belgica — Vol. 70, n° 1, p. 50-52 (2015)
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- Abstract
- An 18-year-old man was referred to the Internal Medicine ward because of a 2-week history of intermittent high fever, weight loss and cough. Clinical examination revealed hepato-splenomegaly and multiple lymph nodes swelling while laboratory tests showed elevated C-reactive protein, gamma glutamyl transferase and lactate dehydrogenase. All serologic testes for auto-immune antibodies, viruses and bacteria were negative except for Chlamydophila pneumoniae. An 18-FDG PET computed tomography scanner showed hypermetabolism in the liver, spleen and lymph nodes. We therefore conducted a liver biopsy that demonstrated non-necrotizing granulomas. We conclude to a C. pneumoniae infection associated with a granulomatous hepatitis. After treatment with Doxyciclin the patient had no more fever, hepatosplenomegaly resolved and blood testes normalized. This case report is to our knowledge the first report of a granulomatous hepatitis associated with C. pneumoniae respiratory infection.
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Citations
Yildiz, H., Wieërs, G., Yombi, J. C., & Marot, J.-C. (2015). Liver granulomatosis: a case of Chlamydophila pneumoniae infection. Acta Clinica Belgica, 70(1), 50-52. https://doi.org/10.1179/2295333714Y.0000000068 (Original work published 2015)