Low-molecular-weight Heparin-induced Skin Necrosis: About 2 Cases

Yombi, Jean Cyr;Belkhir, Leïla;De Baere, Tom;Dubuc, Jean-Emile;Hainaut, Philippe
(2009) Acta Clinica Belgica (Multilingual Edition) — Vol. 64, n° 3, p. 228-230 (2009)

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  • Yombi, Jean CyrUCLouvain
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  • Belkhir, Leïlaorcid-logoUCLouvain
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  • De Baere, TomUCLouvain
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  • Dubuc, Jean-EmileUCLouvain
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  • Hainaut, PhilippeUCLouvain
    Author
Abstract
Heparin-induced skin necrosis is an infrequent condition, complicating unfractionated heparin and more rarely low-molecular-weight heparin administration. Like heparin-induced thrombocytopenia, it is associated with the presence of anti-PF4 antibodies. After reporting 2 observations, we briefly review the clinical features and management of this condition. Early recognition is of the utmost importance since heparin-induced skin necrosis can be associated with HIT, a potentially lethal disorder.
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Yombi, J. C., Belkhir, L., De Baere, T., Dubuc, J.-E., & Hainaut, P. (2009). Low-molecular-weight Heparin-induced Skin Necrosis: About 2 Cases. Acta Clinica Belgica (Multilingual Edition), 64(3), 228-230. https://doi.org/10.1179/acb.2009.040 (Original work published 2009)