Reassessment of stopping power ratio uncertainties caused by mean excitation energies using a water‐based formalism

De Smet, Valérie;Rudi Labarbe;François Vander Stappen;Macq, Benoît;Sterpin, Edmond
(2018) The International Journal of Medical Physics Research and Practice — Vol. 45, n° 7, p. 3361-3370 (2018)

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Abstract
(en) In proton therapy planning, the accuracy of the Stopping Power Ratios (SPR) calculated in the stoichiometric CT calibration is affected by, among others, uncertainties on the mean excitation energies (I‐values) of human tissues and water. Traditionally, the contribution of these uncertainties on the SPR has been conservatively estimated of the order of 1% or more for a reference tissue of known composition. This study provides a methodology that enables a finer estimation of this uncertainty, eventually showing that the traditional estimates of the uncertainty are too conservative.
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De Smet, V., Rudi Labarbe, François Vander Stappen, Macq, B., & Sterpin, E. (2018). Reassessment of stopping power ratio uncertainties caused by mean excitation energies using a water‐based formalism. The International Journal of Medical Physics Research and Practice, 45(7), 3361-3370. https://doi.org/10.1002/mp.12949 (Original work published 2018)