Vesiculopustular eruption in a neonate with trisomy 21 syndrome as a clue of transient myeloproliferative disorders.

Piersigilli, Fiammetta;Diociaiuti, Andrea;Boldrini, Renata;Auriti, Cinzia;Seganti, Giulio;et.al.
(2010) Cutis : cutaneous medicine for the practitioner — Vol. 85, n° 6, p. 286-288 (2010)

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Authors
  • Piersigilli, Fiammettaorcid-logoUCLouvain
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  • Diociaiuti, Andrea
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  • Boldrini, Renata
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  • Auriti, Cinzia
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  • Seganti, Giulio
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Abstract
We report the case of a vesiculopustular eruption associated with a transient myeloproliferative disorder (TMD) in a neonate with trisomy 21 syndrome. Examination of a skin biopsy showed a dermal mixed inflammatory infiltrate including atypical megakaryoblasts. As the white blood cell count spontaneously normalized, the eruption disappeared. This case report and review of the literature demonstrates that a vesiculopustular eruption could be an important clue to identify TMD in a neonate.
Affiliations
  • Bambino Gesù Children’s Hospital – (Italy) RomaDepartment of Neonatology

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Piersigilli, F., Diociaiuti, A., Boldrini, R., Auriti, C., Curci, M., El Hachem, M., & Seganti, G. (2010). Vesiculopustular eruption in a neonate with trisomy 21 syndrome as a clue of transient myeloproliferative disorders. Cutis : cutaneous medicine for the practitioner, 85(6), 286-288. https://hdl.handle.net/2078.5/105500 (Original work published 2010)