Cyclopentenones As Potential Inhibitors of Penicillin Sensitive Enzymes
(1993) Bioorganic & Medicinal Chemistry Letters : the tetrahedron journal for research at the interface of chemistry and biology — Vol. 3, n° 11, p. 2309-2312 (1993)
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- Authors
- Abstract
- 2-cyclopenten-1-ones bearing an acylamino side-chain at C-4 and an acetic acid residue at C-2 were designed as potential alkylating inhibitors of penicillin sensitive enzymes. Compounds 11 and 12 efficiently prepared from the readily available 2-phenylsulfonyl-4-methoxycarbonyl-cyclopentan-1-one 3. They were inactive in all tests.
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Citations
Durand, T., Marchand-Brynaert, J., & Ghosez, L. (1993). Cyclopentenones As Potential Inhibitors of Penicillin Sensitive Enzymes. Bioorganic & Medicinal Chemistry Letters : the tetrahedron journal for research at the interface of chemistry and biology, 3(11), 2309-2312. https://doi.org/10.1016/S0960-894X(01)80945-8 (Original work published 1993)