Trough concentrations of 10–15 mg/L of vancomycin are generally sufficient to achieve pharmacodynamic targets, whereas higher troughs can result in unnecessary nephrotoxicity: we respectfully disagree

Honoré, Patrick;Benkaddour, Yasser;Muscato, Catherine
(2026) Critical Care — Vol. 30, n° 1, p. 420 (2026)

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Honoré, P., Benkaddour, Y., & Muscato, C. (2026). Trough concentrations of 10–15 mg/L of vancomycin are generally sufficient to achieve pharmacodynamic targets, whereas higher troughs can result in unnecessary nephrotoxicity: we respectfully disagree. Critical Care, 30(1), 420. https://doi.org/10.1186/s13054-026-06267-4 (Original work published 2026)