Simultaneous bilateral optic neuropathy and myelitis revealing paraneoplastic neurological syndrome associated with multiple onconeuronal antibodies.

Carette, Timothée;Mulquin, Nicolas;Van Pesch, Vincent;London, Frédéric
(2021) Multiple Sclerosis and Related Disorders — Vol. 49, p. 102789 [1-3] (2021)

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Abstract
Paraneoplastic neurological syndromes (PNS) are immune-mediated complications of cancer associated with a broad spectrum of clinical manifestations. Optic neuropathy (ON) and myelitis are frequent manifestations of multiple sclerosis and neuromyelitis optic spectrum disorders but are considered as non-classical in PNS. Here, we report a case of PNS revealed by simultaneous bilateral ON and myelitis related to a cluster of three neural autoantibodies, in the setting of small cell lung cancer.
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Carette, T., Mulquin, N., Van Pesch, V., & London, F. (2021). Simultaneous bilateral optic neuropathy and myelitis revealing paraneoplastic neurological syndrome associated with multiple onconeuronal antibodies. Multiple Sclerosis and Related Disorders, 49, 102789 [1-3]. https://doi.org/10.1016/j.msard.2021.102789 (Original work published 2021)