Human tumor antigens and cancer immunotherapy
(2015) BioMed Research International — Vol. 2015, p. 1-17 (2015)
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- Abstract
- With the recent developments of adoptive T cell therapies and the use of new monoclonal antibodies against the immune checkpoints, immunotherapy is at a turning point. Key players for the success of these therapies are the cytolytic T lymphocytes, which are a subset of T cells able to recognize and kill tumor cells. Here, I review the nature of the antigenic peptides recognized by these T cells and the processes involved in their presentation. I discuss the importance of understanding how each antigenic peptide is processed in the context of immunotherapy and vaccine delivery.
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Vigneron, N. (2015). Human tumor antigens and cancer immunotherapy. BioMed Research International, 2015, 1-17. https://hdl.handle.net/2078.5/192286 (Original work published 2015)