Telithromycin, a ketolide antibiotic used for the treatment of community-acquired respiratory infections, is widely prescribed in primary care practice. Treatment-related adverse events are mainly of gastrointestinal origin and generally mild in intensity. The authors report the first case of telithromycin-induced severe acute interstitial nephritis. Practitioners should be aware of the possibility that telithromycin therapy could result in this form of drug-induced acute renal failure.
Tintillier, M., Kirch, L., Almpanis, C., Cosyns, J.-P., Pochet, J.-M., & Cuvelier, C. (2004). Telithromycin-induced acute interstitial nephritis: a first case report. American Journal of Kidney Diseases, 44(2), e25-27. https://doi.org/10.1053/j.ajkd.2004.04.045 (Original work published 2004)