Inverted Pyramidal Neurons and Their Axons in the Neocortex of Reeler Mutant Mice

Landrieu, P.;Goffinet, André
(1981) Cell and Tissue Research — Vol. 218, n° 2, p. 293-301 (1981)

Files

pdfdocument.pdf
  • Restricted Access
  • Adobe PDF
  • 2.69 MB
Request a copy

Details

Authors
  • Landrieu, P.UCLouvain
    Author
  • Goffinet, AndréUCLouvain
    Author
Abstract
Inverted pyramidal neurons are very abundant in the cerebral cortex of the adult reeler mutant mouse. Two types of inverted pyramid are found in rapid Golgi impregnations. In the first type the axon starts from the base of the cell body and bends towards the white matter. In the second type, which is more common, the axon emerges from the apical dendritic tree and descends directly towards the white matter. Despite its abnormal topography, the site of origin of the axon in pyramids of the second type displays a normal differentiation, when analysed with the electron microscopic Golgi technique, suggesting that the ectopic initial axon segment is able to fulfil its normal functions.
Affiliations

Citations

  • APA
  • Chicago
  • FWB

Landrieu, P., & Goffinet, A. (1981). Inverted Pyramidal Neurons and Their Axons in the Neocortex of Reeler Mutant Mice. Cell and Tissue Research, 218(2), 293-301. https://doi.org/10.1007/BF00210345 (Original work published 1981)