Physical properties of particles of ipratropium and clenbuterol generatd by equipment suitable for the inhalation of drugs by calves
(1995) Research in Veterinary Science — Vol. 59, n° 2, p. 164-167 (1995)
Files
pdfdocument.pdf
Restricted Access - Adobe PDF
- 473.27 KB
Details
- Authors
- Abstract
- When solutions of ipratropium and clenbuterol were atomised at 300 kPa and 450 kPa in equipment suitable for the inhalation of drugs by calves, the numbers, velocities and diameters of the particles produced were similar. When the pressure was increased to 600 kPa more of the particles were less than 2 microns in diameter and fewer were more than 7 microns in diameter, the fractions of the total mass of the solution generated in these size ranges were similarly increased and decreased, and the velocities of the particles were increased. At any given pressure, the numbers of particles of different sizes, and the proportions of the total mass generated, were similar for the solutions of ipratropium and clenbuterol, but a solution of saline produced more particles with a diameter less than 3 microns. Particles from the solution of ipratropium had the highest velocity and particles from the solution of clenbuterol had the lowest velocity.
- Affiliations
Uliège Faculté de médecine vétérinaire - Physiologie Uliège Department of quantitative methodology University of Tartu Institute of Mathematical Statistics
Citations
Génicot, B., Close, R., Lapp, K., Lindsey, J. K., Lambert, P., & Lekeux, P. (1995). Physical properties of particles of ipratropium and clenbuterol generatd by equipment suitable for the inhalation of drugs by calves. Research in Veterinary Science, 59(2), 164-167. https://doi.org/10.1016/0034-5288(95)90053-5 (Original work published 1995)