Anti-streptavidin antibodies mimicking heterophilic antibodies in thyroid function tests.

Favresse, Julien;Lardinois, Benjamin;Nassogne, Marie-Cécile;Preumont, Vanessa;Gruson, Damien;et.al.
(2018) Clinical Chemistry and Laboratory Medicine : Associated with FESCC and IFCC — Vol. 56, n° 7, p. e160-e163 (2018)

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(en) To the Editor, Hereby we report a rare interference that affected the thyroid function tests in two patients seen in our outpatient clinic between May and June 2017. In our laboratory, thyroid-stimulating hormone (TSH) is measured with a two-site electrochemiluminescent immunoassay (ECLIA) with ruthenium label, whereas free thyroxine (FT4) and free triiodothyronine (FT3) are measured by a competitive ECLIA also using a ruthenium label, both assays being run on a Cobas 8000® e602 module (Roche Diagnostics®, Basel, Switzerland). [...]
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Favresse, J., Lardinois, B., Nassogne, M.-C., Preumont, V., Maiter, D., & Gruson, D. (2018). Anti-streptavidin antibodies mimicking heterophilic antibodies in thyroid function tests. Clinical Chemistry and Laboratory Medicine : Associated with FESCC and IFCC, 56(7), e160-e163. https://doi.org/10.1515/cclm-2017-1027 (Original work published 2018)