Beta-adrenoceptor stimulation potentiates insulin-stimulated PKB phosphorylation in rat cardiomyocytes via cAMP and PKA.

Stuenaes, Jorid T;Bolling, Astrid;Ingvaldsen, Ada;Rommundstad, Camilla;Jensen, Jørgen;et.al.
(2010) British Journal of Pharmacology — Vol. 160, n° 1, p. 116-129 (2010)

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Authors
  • Stuenaes, Jorid T
    Author
  • Bolling, Astrid
    Author
  • Ingvaldsen, Ada
    Author
  • Rommundstad, Camilla
    Author
  • Lai, Yu-ChiangUCLouvain
    Author
  • Jensen, Jørgen
    Author
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Abstract
beta-adrenoceptors are strong regulators of PKB phosphorylation via cAMP and PKA when insulin is present. We hypothesize that PKB mediates important signalling in the heart during beta-adrenergic receptors stimulation.

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Stuenaes, J. T., Bolling, A., Ingvaldsen, A., Rommundstad, C., Sudar, E., Lin, F.-C., Lai, Y.-C., & Jensen, J. (2010). Beta-adrenoceptor stimulation potentiates insulin-stimulated PKB phosphorylation in rat cardiomyocytes via cAMP and PKA. British Journal of Pharmacology, 160(1), 116-129. https://doi.org/10.1111/j.1476-5381.2010.00677.x (Original work published 2010)