Vascular anomalies comprise a heterogeneous group of disorders that are divided into tumors (hemangiomas) and malformations. Recent advances in biomedical research provide insights into the molecular basis of these disorders and a deeper understanding of vascular morphogenesis. In the future, this emerging knowledge will contribute to novel ways to treat vascular anomalies and to regulate pathologic angiogenesis.
Vikkula, M., Boon, L., Mulliken, J. B., & Olsen, B. R. (1998). Molecular basis of vascular anomalies. Trends in Cardiovascular Medicine, 8(7), 281-292. https://doi.org/10.1016/S1050-1738(98)00024-3 (Original work published 1998)