The 12-lead electrocardiogram in anorexia nervosa: A report of 2 cases followed by a retrospective study.
(2001) Journal of Electrocardiology — Vol. 34, n° 3, p. 233-242 (2001)
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- Abstract
- Anorexia nervosa (AN) has been associated with various cardiac disorders and several electrocardiographic abnormalities, the most prominent being sudden death and prolonged QT duration and dispersion. We report 2 cases of AN with marked repolarization abnormalities, the first clearly related to electrolyte imbalance, the second without a good explanation from metabolic, electrolytic or pharmacological sources. A retrospective analysis of 47 other consecutive patients with AN showed that sinus bradycardia was the most common ECG finding, but that QT or QTc interval prolongation was not a typical feature, being present in only 1 patient. The sole variable slightly correlated with QTc duration was the serum potassium concentration. Consequently, marked repolarization changes (QT interval and/or T wave morphology) in AN should not be taken as a feature of the disease, but should call for the search of potential causes such as metabolic and electrolytic disturbances, drug effects, or a possible genetic component.
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Citations
Vanderdonckt, O., Lambert, M., Montero, M. C., Boland, B., & Brohet, C. (2001). The 12-lead electrocardiogram in anorexia nervosa: A report of 2 cases followed by a retrospective study. Journal of Electrocardiology, 34(3), 233-242. https://doi.org/10.1054/jelc.2001.25134 (Original work published 2001)