Concurrent spinal cord and vertebral bone marrow radionecrosis 8 years after therapeutic irradiation.

Warscotte, L.;Duprez, Thierry;Lonneux, Max;Michaux, Lucienne;Lecouvet, Frédéric;et.al.
(2002) Neuroradiology : a journal devoted to neuroimaging and interventional neuroradiology — Vol. 44, n° 3, p. 245-248 (2002)

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Authors
  • Warscotte, L.UCLouvain
    Author
  • Duprez, ThierryUCLouvain
    Author
  • Lonneux, MaxUCLouvain
    Author
  • Michaux, LucienneUCLouvain
    Author
  • Renard, LaurentUCLouvain
    Author
  • Sindic, ChristianUCLouvain
    Author
  • Author
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Abstract
Concurrent radionecrosis within the spinal cord and the bone marrow at the same thoracic level was observed 8 years after localized therapeutic irradiation in a patient who had undergone repeated cycles of radiotherapy, glucocorticoid treatment, and chemotherapy for a non-Hodgkin's lymphoma. Mechanisms combining radiotoxic potentialization by glucocorticoids/alkylating agents and delayed radiation-induced vasculitis involving the common arterial pathways to the spinal cord and to the vertebrae were speculated to have acted in a synergistic way.
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Citations

Warscotte, L., Duprez, T., Lonneux, M., Michaux, L., Renard, L., Sindic, C., & Lecouvet, F. (2002). Concurrent spinal cord and vertebral bone marrow radionecrosis 8 years after therapeutic irradiation. Neuroradiology : a journal devoted to neuroimaging and interventional neuroradiology, 44(3), 245-248. https://doi.org/10.1007/s002340100677 (Original work published 2002)