Concurrent radionecrosis within the spinal cord and the bone marrow at the same thoracic level was observed 8 years after localized therapeutic irradiation in a patient who had undergone repeated cycles of radiotherapy, glucocorticoid treatment, and chemotherapy for a non-Hodgkin's lymphoma. Mechanisms combining radiotoxic potentialization by glucocorticoids/alkylating agents and delayed radiation-induced vasculitis involving the common arterial pathways to the spinal cord and to the vertebrae were speculated to have acted in a synergistic way.
Warscotte, L., Duprez, T., Lonneux, M., Michaux, L., Renard, L., Sindic, C., & Lecouvet, F. (2002). Concurrent spinal cord and vertebral bone marrow radionecrosis 8 years after therapeutic irradiation. Neuroradiology : a journal devoted to neuroimaging and interventional neuroradiology, 44(3), 245-248. https://doi.org/10.1007/s002340100677 (Original work published 2002)