Reply to Polverino: Deconvoluting Chronic Obstructive Pulmonary Disease: Are B Cells the Frontrunners?
(2019) American Journal of Respiratory and Critical Care Medicine — Vol. 199, n° 9, p. 1171-1172 (2019)
Files
2019_Ladjemi_Am_J_Respir_Crit_Care_Med.pdf
Open Access - Adobe PDF
- 844.99 KB
Details
- Authors
Ladjemi, Maha Zohra 
- Abstract
- From the Authors: We thank Dr. Polverino for her letter and interest in our recently published study on IgA production in lymphoid follicles (LFs) from patients with chronic obstructive pulmonary disease (COPD) (1), as well as for her inspiring and stimulating thoughts. Our data show that IgA production occurs in LFs that are present around bronchioles from patients with severe COPD, highlighting the key contribution of the small airways to COPD pathophysiology (2, 3), as well as the relevance of B-cell activation in emphysema, as discussed by Dr. Polverino. [...]
- Affiliations
Citations
Ladjemi, M. Z., Burgel, P. R., & Pilette, C. (2019). Reply to Polverino: Deconvoluting Chronic Obstructive Pulmonary Disease: Are B Cells the Frontrunners? American Journal of Respiratory and Critical Care Medicine, 199(9), 1171-1172. https://doi.org/10.1164/rccm.201812-2249LE (Original work published 2019)