Hepatic mesenchymal hamartoma is a rare benign tumour in children. It is often large and centrally located in the liver at diagnosis, making surgical resection difficult; thus non-radical resection has been proposed in the past as acceptable management. However, a literature survey and a case with recurrence associated with cytogenetic anomalies suggest that radical liver surgery (resection with a margin of normal liver parenchyma, as for malignant tumour) should be recommended for mesenchymal hamartoma.
Sharif, K., Ramani, P., Lochbuhler, H., Grundy, R., & de Ville de Goyet, J. (2006). Recurrent mesenchymal hamartoma associated with 19q translocation. A call for more radical surgical resection. European Journal of Pediatric Surgery, 16(1), 64-67. https://doi.org/10.1055/s-2005-873072 (Original work published 2006)