Insight into the medicinal chemistry of the endocannabinoid hydrolase inhibitors.
(2013) Current Medicinal Chemistry — Vol. 20, n° 14, p. 1824-1846 (2013)
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- Abstract
- Endocannabinoid hydrolases are nowadays increasingly considered as potential therapeutic targets for treating several pathological states. So far, numerous classes of endocannabinoid hydrolase inhibitors have been described. We herein review the medicinal chemistry of these inhibitors with a particular emphasis on the basis of their design, chemical structure, structure-activity relationships, and inhibition mechanisms.
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Kapanda Nankwa, C., Poupaert, J., & Lambert, D. (2013). Insight into the medicinal chemistry of the endocannabinoid hydrolase inhibitors. Current Medicinal Chemistry, 20(14), 1824-1846. https://doi.org/10.2174/09298673113209990108 (Original work published 2013)