Normal-pregnancy in Primary Alveolar Hypoventilation Treated With Nocturnal Nasal Intermittent Positive Pressure Ventilation
(1995) The European Respiratory Journal — Vol. 8, n° 8, p. 1424-1427 (1995)
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- Abstract
- Nocturnal nasal intermittent positive pressure ventilation (NIPPV) is increasingly used to treat chronic respiratory failure in a wide variety of conditions (myopathies, Ondine's curse, kyphoscoliosis, etc.) and allows a normal everyday life. Some of these diseases affect women of childbearing age. We report on a young woman suffering from primary alveolar hypoventilation, who presented with limitation of daytime activities, severe oxygen desaturation during sleep, polycythaemia and pulmonary hypertension. These abnormalities completely reversed after a few months of NIPPV applied through a nasal mask. Whilst under ventilatory assistance during sleep, she had an uneventful pregnancy and delivery of a normal baby. We suggest that in selected patients requiring NIPPV, pregnancy can be contemplated with a reasonable level of safety both for the mother and the child, provided that adequate mechanical ventilatory assistance during sleep is maintained throughout pregnancy.
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Pieters, T., Aubert, G., Collard, P., Amy, JJ., Burrini, D., & Rodenstein, D. (1995). Normal-pregnancy in Primary Alveolar Hypoventilation Treated With Nocturnal Nasal Intermittent Positive Pressure Ventilation. The European Respiratory Journal, 8(8), 1424-1427. https://doi.org/10.1183/09031936.95.08081424 (Original work published 1995)