Reliability and agreement of proton density-weighted vs. gadolinium-enhanced T1-weighted MRI in hand osteoarthritis. An OMERACT MRI special interest group reliability exercise.

Maugesten, Øystein;Pedersen, Susanne J;Stoenoiu, Maria;Kroon, Féline P B;Haugen, Ida K;et.al.
(2021) Seminars in Arthritis and Rheumatism — Vol. 51, n° 4, p. 929-932 (2021)

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Authors
  • Maugesten, Øystein
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  • Pedersen, Susanne J
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  • Stoenoiu, Mariaorcid-logoUCLouvain
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  • Kroon, Féline P B
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  • Haugen, Ida K
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Abstract
To compare reliabilities of assessing synovitis in hand osteoarthritis (OA) using Magnetic Resonance Imaging (MRI) with/without gadolinium (Gd). Three readers scored synovitis on non-enhanced two-dimensional (2D) proton density (PD)-weighted MRI and Gd-enhanced (3D) MRI of hand joints in 20 patients. Inter-reader reliabilities were examined. Reliability was good for Gd-enhanced MRI, but poor for non-enhanced PD-weighted MRI (intraclass correlation coefficient 0.83 and 0.21, respectively). Agreement between the two sequences was poor (weighted kappa 0.18). Gd-enhanced MRI was more reliable than PD-weighted MRI for assessing synovitis. Gd-enhancement, but also resolution and tissue contrast, might have contributed to this.
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Maugesten, Ø., Pedersen, S. J., Stoenoiu, M., Kroon, F. P. B., Mathew, A. J., Genant, H. K., Conaghan, P. G., Gandjbakhch, F., Kloppenburg, M., Peterfy, C., Østergaard, M., & Haugen, I. K. (2021). Reliability and agreement of proton density-weighted vs. gadolinium-enhanced T1-weighted MRI in hand osteoarthritis. An OMERACT MRI special interest group reliability exercise. Seminars in Arthritis and Rheumatism, 51(4), 929-932. https://doi.org/10.1016/j.semarthrit.2021.05.007 (Original work published 2021)