Functionalized Orthoesters as Powerful Building Blocks for the Efficient Preparation of Heteroaromatic Bicycles

Bastug, Gulluzar;Eviolitte, Christophe;Marko, Istvan
(2012) Organic Letters — Vol. 14, n° 13, p. 3502-3505 (2012)

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  • Bastug, GulluzarUCLouvain
    Author
  • Eviolitte, ChristopheUCLouvain
    Author
  • Marko, IstvanUCLouvain
    Author
Abstract
By combining substituted anilines with functionalized orthoesters, an efficient and connective methodology for the preparation of benzoxazole, benzothiazole, and benzimidazole derivatives has been established. The versatility of this approach enables the development of new libraries of heterocycles containing multifunctional sites.
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Bastug, G., Eviolitte, C., & Marko, I. (2012). Functionalized Orthoesters as Powerful Building Blocks for the Efficient Preparation of Heteroaromatic Bicycles. Organic Letters, 14(13), 3502-3505. https://doi.org/10.1021/ol301472a (Original work published 2012)