Allergic contact dermatitis from povidone-iodine: a re-evaluation study.
(2005) Contact dermatitis — Vol. 52, n° 1, p. 9-10 (2005)
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- Abstract
- 500 consecutive patients were patch tested with a 10% povidone-iodine (PVP-I) solution, diluted 10 times in water. Readings were made at 2 and 4 days. 14 of the 500 (2.8%) showed a positive test to PVP-I. The 14 positive patients to PVP-I were subjected to a repeated open application test (ROAT) with a PVP-I solution, as is; 2 of the 14 were recorded as positive. It was concluded that only 2 of the 500 patients had true allergic contact dermatitis from PVP-I (0.4%). This study emphasizes the need for more complete investigation, when testing with some allergens, when they share both irritant and allergenic properties, such as PVP-I. The approach is important to rule out false-positive patch test reactions and to assess true clinical relevance.
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Lachapelle, J.-M. (2005). Allergic contact dermatitis from povidone-iodine: a re-evaluation study. Contact dermatitis, 52(1), 9-10. https://doi.org/10.1111/j.0105-1873.2005.00479.x (Original work published 2005)